داروساز ایرانی

Foreword . . . . . . . . . . . . . . . . . . . . . xv
Foreword to the First Edition . . . . . . . . . . . xvii
Preface. . . . . . . . . . . . . . . . . . . . . . xix
Contributors . . . . . . . . . . . . . . . . . . . xxi
Guiding Principles of Pharmacotherapy. . . . . xxxiii
SECTION 1: BASIC CONCEPTS. . . . . . . . . 1
L. Michael Posey, Section Editor
1. Pharmacoeconomics: Principles, Methods,
and Applications. . . . . . . . . . . . . . . 1
Lisa A. Sanchez
2. Health Outcomes and Quality of Life . . . . 17
Stephen Joel Coons
3. Evidence-Based Medicine. . . . . . . . . . 27
Elaine Chiquette
L. Michael Posey
4. Documentation of Pharmacy
Services . . . . . . . . . . . . . . . . . . 39
George E. MacKinnon, III
Neil J. MacKinnon
5. Clinical Pharmacokinetics
and Pharmacodynamics. . . . . . . . . . . 51
Larry A. Bauer
6. Pharmacogenetics. . . . . . . . . . . . . . 75
Larisa H. Cavallari
Y. W. Francis Lam
7. Pediatrics. . . . . . . . . . . . . . . . . . 91
Milap C. Nahata
Carol Taketomo
8. Geriatrics . . . . . . . . . . . . . . . . . 103
Catherine I. Lindblad
Shelly L. Gray
David R. P. Guay
Emily R. Hajjar
Teresa C. McCarthy
Joseph T. Hanlon
9. Pharmacoepidemiology . . . . . . . . . . 115
Andy Stergachis
Thomas K. Hazlet
10. Clinical Toxicology . . . . . . . . . . . . 125
Peter A. Chyka
SECTION 2. CARDIOVASCULAR
DISORDERS . . . . . . . . . . . 149
Robert L. Talbert, Section Editor
11. Cardiovascular Testing. . . . . . . . . . . 149
Robert L. Talbert
12. Cardiopulmonary Resuscitation. . . . . . .171
Jeffrey F. Barletta
13. Hypertension . . . . . . . . . . . . . . . 185
Joseph J. Saseen
Barry L. Carter
14. Heart Failure. . . . . . . . . . . . . . . .219
Robert B. Parker
J. Herbert Patterson
Julie A. Johnson
15. Ischemic Heart Disease . . . . . . . . . . 261
Robert L. Talbert
16. Acute Coronary Syndromes . . . . . . . . 291
Sarah A. Spinler
Simon de Denus
17. Arrhythmias. . . . . . . . . . . . . . . . 321
Jerry L. Bauman
Marieke Dekker Schoen
18. Diastolic Heart Failure and
the Cardiomyopathies . . . . . . . . . . . 357
Jean M. Nappi
Michael R. Zile
19. Venous Thromboembolism. . . . . . . . . 373
Stuart T. Haines
Mario Zeolla
Daniel M. Witt
20. Stroke. . . . . . . . . . . . . . . . . . . 415
Susan C. Fagan
David C. Hess
21. Hyperlipidemia . . . . . . . . . . . . . . 429
Robert L. Talbert
22. Peripheral Arterial Disease. . . . . . . . . 453
Barbara J. Hoeben
Robert L. Talbert
23. Use of Vasopressors and Inotropes in the
Pharmacotherapy of Shock. . . . . . . . . 461
Maria I. Rudis
Joseph F. Dasta
24. Hypovolemic Shock . . . . . . . . . . . . 479
Brian L. Erstad
SECTION 3. RESPIRATORY
DISORDERS . . . . . . . . . . . 495
Robert L. Talbert, Section Editor
25. Introduction to Pulmonary Function
Testing . . . . . . . . . . . . . . . . . . 495
Jay I. Peters
Stephanie M. Levine
26. Asthma . . . . . . . . . . . . . . . . . . 503
H. William Kelly
Christine A. Sorkness
27. Chronic Obstructive Pulmonary Disease . . 537
Sharya V. Bourdet
Dennis M. Williams
28. Acute Respiratory Distress Syndrome. . . .557
Peter Gal
J. Laurence Ransom
29. Drug-Induced Pulmonary Diseases. . . . . 577
Hengameh H. Raissy
Michelle Harkins
Patricia L. Marshik
30. Cystic Fibrosis. . . . . . . . . . . . . . . 591
Gary Milavetz
Jeffrey J. Smith
SECTION 4. GASTROINTESTINAL
DISORDERS . . . . . . . . . . . 605
Joseph T. DiPiro, Section Editor
31. Evaluation of the Gastrointestinal
Tract . . . . . . . . . . . . . . . . . . . 605
Marie A. Chisholm
Mark W. Jackson
32. Gastroesophageal Reflux Disease. . . . . . 613
Dianne B. Williams
Robert R. Schade
33. Peptic Ulcer Disease. . . . . . . . . . . . 629
Rosemary R. Berardi
Lynda S. Welage
34. Inflammatory Bowel Disease. . . . . . . . 649
Joseph T. DiPiro
Robert R. Schade
35. Nausea and Vomiting. . . . . . . . . . . .665
Cecily V. DiPiro
A. Thomas Taylor
36. Diarrhea, Constipation, and Irritable
Bowel Syndrome. . . . . . . . . . . . . .677
William J. Spruill
William E. Wade
37. Portal Hypertension and Cirrhosis . . . . . 693
Edward G. Timm
James J. Stragand
38. Drug-Induced Liver Disease . . . . . . . . 713
William R. Kirchain
Mark A. Gil
39. Pancreatitis . . . . . . . . . . . . . . . . 721
Rosemary R. Berardi
Patricia A. Montgomery
40. Viral Hepatitis. . . . . . . . . . . . . . . 737
Manjunath P. Pai
Renee-Claude Mercier
Marsha A. Raebel
SECTION 5. RENAL DISORDERS. . . . . . . 761
Gary R. Matzke, Section Editor
41. Quantification of Renal Function. . . . . . 761
Thomas C. Dowling
Thomas J. Comstock
42. Acute Renal Failure . . . . . . . . . . . . 781
Bruce A. Mueller
43. Chronic Kidney Disease: Progression-
Modifying Therapies. . . . . . . . . . . . 799
Melanie S. Joy
Abhijit Kshirsagar
James Paparello
44. Chronic Kidney Disease: Therapeutic
Approach for the Management of
Complications. . . . . . . . . . . . . . . 821
Joanna Q. Hudson
Kunal Chaudhary
45. Hemodialysis and Peritoneal Dialysis. . . . 851
Rowland J. Elwell
Edward F. Foote
46. Drug-Induced Kidney Disease . . . . . . . 871
Thomas D. Nolin
Jonathan Himmelfarb
Gary R. Matzke
47. Glomerulonephritis . . . . . . . . . . . . 891
Alan H. Lau
48. Drug Therapy Individualization for Patients
with Renal Insufficiency . . . . . . . . . . 919
Reginald F. Frye
Gary R. Matzke
49. Disorders of Sodium, Water, Calcium, and
Phosphorus Homeostasis. . . . . . . . . . 937
Melanie S. Joy
Gerald A. Hladik
50. Disorders of Potassium and Magnesium
Homeostasis. . . . . . . . . . . . . . . . 967
Donald F. Brophy
Todd W. B. Gehr
51. Acid-Base Disorders. . . . . . . . . . . . 983
Gary R. Matzke
Paul M. Palevsky
SECTION 6. NEUROLOGIC DISORDERS. . 1003
Barbara G. Wells, Section Editor
52. Evaluation of Neurologic Illness. . . . . .1003
Susan C. Fagan
Fenwick T. Nichols
53. Multiple Sclerosis . . . . . . . . . . . . 1007
Jacquelyn L. Bainbridge
John R. Corboy
54. Epilepsy . . . . . . . . . . . . . . . . . 1023
Barry E. Gidal
William R. Garnett
55. Status Epilepticus. . . . . . . . . . . . .1049
Stephanie J. Phelps
Collin A. Hovinga
Bradley A. Boucher
56. Acute Management of the Brain Injury
Patient. . . . . . . . . . . . . . . . . . 1061
Bradley A. Boucher
Stephanie J. Phelps
Shelly D. Timmons
57. Parkinson’s Disease. . . . . . . . . . . .1075
Merlin V. Nelson
Richard C. Berchou
Peter A. LeWitt
58. Pain Management. . . . . . . . . . . . .1089
Terry J. Baumann
59. Headache Disorders. . . . . . . . . . . .1105
Deborah S. King
Katherine C. Herndon
SECTION 7. PSYCHIATRIC DISORDERS. . 1123
Barbara G. Wells, Section Editor
60. Evaluation of Psychiatric Illness. . . . . . 1123
Patricia A. Marken
Mark E. Schneiderhan
Stuart Munro
61. Childhood Disorders . . . . . . . . . . . 1133
Julie A. Dopheide
Karen A. Theesen
Michael Malkin
62. Eating Disorders . . . . . . . . . . . . . 1147
Patricia A. Marken
Roger W. Sommi
63. Alzheimer’s Disease . . . . . . . . . . . 1157
Jennifer D. Faulkner
Jody Bartlett
Paul Hicks
64. Substance-Related Disorders: Overview
and Depressants, Stimulants, and
Hallucinogens . . . . . . . . . . . . . . 1175
Paul L. Doering
65. Substance-Related Disorders: Alcohol,
Nicotine, and Caffeine . . . . . . . . . . 1193
Paul L. Doering
66. Schizophrenia . . . . . . . . . . . . . . 1209
M. Lynn Crismon
Peter F. Buckley
67. Depressive Disorders. . . . . . . . . . . 1235
Judith C. Kando
Barbara G. Wells
Peggy E. Hayes
68. Bipolar Disorder . . . . . . . . . . . . . 1257
Martha P. Fankhauser
Marlene P. Freeman
69. Anxiety Disorders I: Generalized Anxiety,
Panic, and Social Anxiety Disorders. . . . 1285
Cynthia K. Kirkwood
Sarah T. Melton
70. Anxiety Disorders II: Posttraumatic Stress
Disorder and Obsessive-Compulsive
Disorder . . . . . . . . . . . . . . . . . 1307
Cynthia K. Kirkwood
Eugene H. Makela
Barbara G. Wells
71. Sleep Disorders. . . . . . . . . . . . . . 1321
Cherry W. Jackson
Judy L. Curtis
SECTION 8. ENDOCRINOLOGIC
DISORDERS. . . . . . . . . . .1333
Robert L. Talbert, Section Editor
72. Diabetes Mellitus. . . . . . . . . . . . . 1333
Curtis L. Triplitt
Charles A. Reasner
William L. Isley
73. Thyroid Disorders . . . . . . . . . . . . 1369
Robert L. Talbert
74. Adrenal Gland Disorders . . . . . . . . . 1391
John G. Gums
John M. Tovar
75. Pituitary Gland Disorders. . . . . . . . . 1407
Amy M. Heck
Jack A. Yanovski
Karim Anton Calis
SECTION 9. GYNECOLOGIC AND
OBSTETRIC DISORDERS . . . 1425
Barbara G. Wells, Section Editor
76. Pregnancy and Lactation: Therapeutic
Considerations . . . . . . . . . . . . . . 1425
Denise L. Walbrandt Pigarelli
Connie K. Kraus
Beth E. Potter
77. Contraception . . . . . . . . . . . . . . 1443
Lori M. Dickerson
Kathryn K. Bucci
78. Menstruation-Related Disorders. . . . . . 1465
Martha P. Fankhauser
Marlene P. Freeman
79. Endometriosis . . . . . . . . . . . . . . 1485
Deborah A. Sturpe
Alkesh D. Patel
80. Hormone Therapy in Women . . . . . . . 1493
Sophia N. Kalantaridou
Susan R. Davis
Karim Anton Calis
SECTION 10. UROLOGIC DISORDERS. . . 1515
L. Michael Posey, Section Editor
81. Erectile Dysfunction . . . . . . . . . . . 1515
Mary Lee
82. Management of Benign Prostatic
Hyperplasia . . . . . . . . . . . . . . . 1535
Mary Lee
83. Urinary Incontinence. . . . . . . . . . . 1547
Eric S. Rovner
Jean Wyman
Thomas Lackner
David Guay
SECTION 11. IMMUNOLOGIC
DISORDERS. . . . . . . . . . 1565
Gary C. Yee, Section Editor
84. Function and Evaluation of the Immune
System. . . . . . . . . . . . . . . . . . 1565
Philip D. Hall
Mary S. Hayney
85. Systemic Lupus Erythematosus and Other
Collagen-Vascular Diseases. . . . . . . . 1581
Jeffrey C. Delafuente
Kimberly A. Cappuzzo
86. Allergic and Pseudoallergic Drug
Reactions. . . . . . . . . . . . . . . . .1599
Joseph T. DiPiro
Dennis R. Ownby
87. Solid-Organ Transplantation . . . . . . . 1613
Heather J. Johnson
Kristine S. Schonder
SECTION 12. BONE AND JOINT
DISORDERS. . . . . . . . . . 1645
L. Michael Posey, Section Editor
88. Osteoporosis and Osteomalacia . . . . . . 1645
Mary Beth O’Connell
Terry L. Seaton
89. Rheumatoid Arthritis. . . . . . . . . . . 1671
Arthur A. Schuna
90. Osteoarthritis. . . . . . . . . . . . . . . 1685
Karen E. Hansen
Mary Elizabeth Elliott
91. Gout and Hyperuricemia . . . . . . . . . 1705
David W. Hawkins
Daniel W. Rahn
SECTION 13. DISORDERS OF THE
EYES, EARS, NOSE,
AND THROAT . . . . . . . . . 1713
L. Michael Posey, Section Editor
92. Glaucoma . . . . . . . . . . . . . . . . 1713
Timothy S. Lesar
Richard G. Fiscella
Deepak Edward
93. Allergic Rhinitis . . . . . . . . . . . . . 1729
J. Russell May
Philip H. Smith
SECTION 14. DERMATOLOGIC
DISORDERS. . . . . . . . . . 1741
L. Michael Posey, Section Editor
94. Dermatologic Drug Reactions,
Self-Treatable Skin Disorders, and Skin
Cancer. . . . . . . . . . . . . . . . . . 1741
Nina H. Cheigh
95. Acne Vulgaris . . . . . . . . . . . . . . 1755
Dennis P. West
Lee E. West
Maria Letizia Musumeci
Giuseppe Micali
96. Psoriasis . . . . . . . . . . . . . . . . . 1769
Dennis P. West
Lee E. West
Laura Scuderi
Giuseppe Micali
97. Atopic Dermatitis. . . . . . . . . . . . .1785
Nina H. Cheigh
SECTION 15. HEMATOLOGIC
DISORDERS. . . . . . . . . . 1793
Gary C. Yee, Section Editor
98. Hematopoiesis . . . . . . . . . . . . . . 1793
William P. Petros
Solveig Ericson
99. Anemias . . . . . . . . . . . . . . . . . 1805
Beata Ineck
Barbara J. Mason
E. Gregory Thompson
100. Coagulation Disorders . . . . . . . . . . 1833
Betsy Bickert
Janet L. Kwiatkowski
101. Sickle Cell Disease. . . . . . . . . . . . 1855
C. Y. Jennifer Chan
Reginald Moore
102. Drug-Induced Hematologic Disorders. . . 1875
S. Jay Weaver
Thomas E. Johns
SECTION 16. INFECTIOUS DISEASES . . . 1891
Joseph T. DiPiro, Section Editor
103. Laboratory Tests to Direct Antimicrobial
Pharmacotherapy. . . . . . . . . . . . . 1891
Michael J. Rybak
Jeffrey R. Aeschlimann
104. Antimicrobial Regimen Selection . . . . . 1909
David S. Burgess
Betty J. Abate
105. Central Nervous System Infections . . . . 1923
Elizabeth D. Hermsen
John C. Rotschafer
106. Lower Respiratory Tract Infections . . . . 1943
Mark L. Glover
Michael D. Reed
107. Upper Respiratory Tract Infections . . . . 1963
Yasmin Khaliq
Sarah Forgie
George Zhanel
108. Skin and Soft Tissue Infections . . . . . . 1977
Susan L. Pendland
Douglas N. Fish
Larry H. Danziger
109. Infective Endocarditis. . . . . . . . . . . 1997
Michael A. Crouch
Angie Veverka
110. Tuberculosis . . . . . . . . . . . . . . . 2015
Charles A. Peloquin
111. Gastrointestinal Infections and
Enterotoxigenic Poisonings. . . . . . . . 2035
Steven Martin
Rose Jung
112. Intraabdominal Infections. . . . . . . . . 2055
Joseph T. DiPiro
Thomas R. Howdieshell
113. Parasitic Diseases. . . . . . . . . . . . . 2067
JV Anandan
114. Urinary Tract Infections and Prostatitis . . 2081
Elizabeth A. Coyle
Randall A. Prince
115. Sexually Transmitted Diseases . . . . . . 2097
Leroy C. Knodel
116. Bone and Joint Infections. . . . . . . . . 2119
Edward P. Armstrong
Leslie L. Barton
117. Sepsis and Septic Shock . . . . . . . . . 2131
S. Lena Kang-Birken
Joseph T. DiPiro
118. Superficial Fungal Infections . . . . . . . 2145
Thomas E. R. Brown
Thomas W. F. Chin
119. Invasive Fungal Infections. . . . . . . . .2161
Peggy L. Carver
120. Infections in Immunocompromised
Patients. . . . . . . . . . . . . . . . . .2191
Douglas N. Fish
S. Diane Goodwin
121. Antimicrobial Prophylaxis in Surgery . . . 2217
Salmaan Kanji
John W. Devlin
122. Vaccines, Toxoids, and Other
Immunobiologics. . . . . . . . . . . . . 2231
Mary S. Hayney
123. Human Immunodeficiency Virus
Infection. . . . . . . . . . . . . . . . . 2255
Courtney V. Fletcher
Thomas N. Kakuda
SECTION 17. ONCOLOGIC DISORDERS. . 2279
Gary C. Yee, Section Editor
124. Cancer Treatment and Chemotherapy . . . 2279
Carol McManus Balmer
Amy Wells Valley
Andrea Iannucci
125. Breast Cancer . . . . . . . . . . . . . . 2329
Celeste Lindley
Laura Boehnke Michaud
126. Lung Cancer . . . . . . . . . . . . . . . 2365
Rebecca S. Finley
Jeannine S. McCune
127. Colorectal Cancer. . . . . . . . . . . . .2383
Patrick J. Medina
Lisa E. Davis
128. Prostate Cancer. . . . . . . . . . . . . . 2421
Jill M. Kolesar
129. Lymphomas . . . . . . . . . . . . . . . 2439
Val R. Adams
Gary C. Yee
130. Ovarian Cancer. . . . . . . . . . . . . . 2467
William C. Zamboni
Laura L. Jung
Margaret E. Tonda
131. Acute Leukemias. . . . . . . . . . . . . 2485
Helen L. Leather
Betsy Bickert
132. Chronic Leukemias. . . . . . . . . . . . 2513
Timothy R. McGuire
Steven Z. Pavletic
133. Melanoma . . . . . . . . . . . . . . . . 2525
Rowena N. Schwartz
134. Hematopoietic Stem Cell
Transplantation. . . . . . . . . . . . . . 2541
Janelle B. Perkins
Gary C. Yee
SECTION 18. NUTRITIONAL
DISORDERS. . . . . . . . . . 2559
Gary R. Matzke, Section Editor
135. Assessment of Nutrition Status and
Nutrition Requirements. . . . . . . . . . 2559
Katherine Hammond Chessman
Vanessa J. Kumpf
136. Prevalence and Significance of
Malnutrition . . . . . . . . . . . . . . . 2579
Gordon Sacks
Pamela D. Reiter
137. Parenteral Nutrition. . . . . . . . . . . . 2591
Todd W. Mattox
Pamela D. Reiter
138. Enteral Nutrition . . . . . . . . . . . . . 2615
Vanessa J. Kumpf
Katherine Hammond Chessman
139. Nutritional Considerations in
Major Organ Failure . . . . . . . . . . . 2635
Renee M. DeHart
Sunshine J. Yocum
140. Obesity. . . . . . . . . . . . . . . . . .2659
John V. St. Peter
Mehmood A. Khan
Glossary . . . . . . . . . . . . . . . . . . . . 2677
Index. . . . . . . . . . . . . . . . . . . . . . 2695
Color plates . . . . . . . . . . . . . . . . . . 2803